Below are the bare bones settings for the web-HUMAN 6 experimental navigator that will allow users to reproduce the experiment of interest.
I. Response to moderate exercise
Below are the bare bones settings for the web-HUMAN
6 experimental navigator that will allow users to reproduce the experiment.
| View Output: | |||||
| COL | O2DEBT | MFLOL | VENT | ||
| as: graph | graph | graph | graph | ||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| EXER | 1.5 | L/M |
| XERMIN | 1H* | time min. |
| Run Experiment: |
| for 60 minutes at 5 minute intervals |
* H = hours & D = Days
Show me the output of these model settings
II. Response to high altitude
Below are the
bare bones settings for the web-HUMAN 6 experimental navigator that
will allow users to reproduce the experiment.
| View Output: | |||||
| PO2A | PCO2A | PH | VENT | BICARB | |
| as: graph | graph | graph | graph | graph | |
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| BAROP | 480 | mmHG |
| Choose | ||
| Run Experiment: |
| for 7D minutes at 12H minute intervals |
* H = hours & D = Days
Show me the output of these model settings
III. Fever- a response to
a new set point
Below
are the bare bones settings for the web-HUMAN 6 experimental navigator
that will allow users to reproduce the experiment.
| View Output: | |||||
| SWETV | TEMP | SHIV | |||
| as: graph | graph | graph | |||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| TEMSET | 39 | deg. C |
| Choose | ||
| Run Experiment: |
| for 5H minutes at 30 minute intervals |
* H = hours & D = Days
Show me the output of these model settings
IV. Create Physiologic Pathology-
Pheochromocytoma
Below are
the bare bones settings for the web-HUMAN 6 experimental navigator that
will allow users to reproduce the experiment.
| View Output: | |||||
| AP | PULSE | VENT | BMR | SWETV | SYMPNA |
| as: graph | graph | graph | graph | graph | graph |
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| PHEO | 1.6 | 0=none 3=severe |
| Choose | ||
| Run Experiment: |
| for 120 minutes at 30 minute intervals |
* H = hours & D = Days
Show me the output of these model settings
V. Kidney induced volume
retention
Below are
the bare bones settings for the web-HUMAN 6 experimental navigator that
will allow users to reproduce the experiment.
| View Output: | |||||
| RENPP | AP | BV | ALDO | UNA | |
| as: graph | graph | graph | graph | graph | |
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| CLAMP | 40 | added mmHg |
| Choose | ||
| Run Experiment: |
| for 5D minutes at 12H minute intervals |
* H = hours & D = Days
Show me the output of these model settings
VI. Anemia - progressive
reduction in resistance yields progressive increase in flow
[ Flow = Conductance * Driving pressure]
Below are
the bare bones settings for the web-HUMAN 6 experimental navigator that
will allow users to reproduce the experiment.
| View Output: | |||||
| CO | COND | AP | |||
| as: graph | graph | graph | |||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| ERYTHB | 0.0 | times normal |
| Choose | ||
| Run Experiment: |
| for 31D minutes at 2D minute intervals |
* H = hours & D = Days
Show me the output of these model settings
VII. Physiologic
Pharmacology- Response to alpha adrenergic blockade
Below are
the bare bones settings for the web-HUMAN 6 experimental navigator that
will allow users to reproduce the experiment.
| View Output: | |||||
| AP | TPR | SKNFLO | COND | ||
| as: graph | graph | graph | graph | ||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| PHOXY | 10 | to 60mg/day, contin. |
| Choose | ||
| Run Experiment: |
| for 12H minutes at 60 minute intervals |
* H = hours & D = Days
Show me the output of these model settings
VIII. Create
Physiologic Pathology- Uremic response to kidney 'removal'
(decrease working functional mass of kidney)
Below
are the bare bones settings for the web-HUMAN 6 experimental navigator
that will allow users to reproduce the experiment.
| View Output: | |||||
| BUN | UPR | ||||
| as: graph | graph | ||||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| REMASS | 0.5 | times normal |
| Choose | ||
| Run Experiment: |
| for 1D minutes at 120 minute intervals |
* H = hours & D = Days
Show me the output of these model settings
IX. Response to dialysis
of a uremic kidney- HUMAN's artificial organs
Below
are the bare bones settings for the web-HUMAN 6 experimental navigator
that will allow users to reproduce the experiment.
A. Step #1- Create a uremic kidney (see setup VIII. directly above)
B. Step #2- Dialyze the uremic kidney
| View Output: | |||||
| BUN | PNA | BICARB | |||
| as: graph | graph | graph | |||
| Experiment Controls: | ||
| Change Variable | Enter New Value | Info On Variable |
| DIAL | 1.0 | 0=no 1=dialyze 8 hr. |
| Choose | ||
| Run Experiment: |
| for 8H minutes at 60 minute intervals |
Show me the output of these model settings